Focus sur quelques publications du Département Sciences Biologiques et Médicales |
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To specifically inhibit therapeutic target as HIV-1 integrase and human Topoisomerase 1 V. Parissi, MFP Bordeaux, P. Pourquier IRC Montpellier, I. Huc, LMU Munich |
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CRISPR-Cas9 genome editing induces megabase-scale chromosomal truncations. Biotherapy team, U1035. Cullot et al., Nat Commun. 2019
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http://onlinelibrary.wiley.com/doi/10.1002/hep4.1029/full New insights into diagnosis and therapeutic options for proliferative hepatoblastoma : http://onlinelibrary.wiley.com/wol1/doi/10.1002/hep.29672/abstract
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Functional interactions between retroviral integration complexes and host chromatin unveiled |
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“Interaction between the Flagellar Pocket Collar and the Hook Complex via a Novel Microtubule-Binding Protein in Trypanosoma Brucei” PLOS Pathogens 13, no. 11 (November 1, 2017): e1006710, |
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Multi-layered control of autophagy during adenovirus cell entry through a conserved PPxY motif L’Adénovirus limite l’autophagie induite par les dommages membranaires grâce au motif conservé PPxY de la protéine de capside PVI. Charlotte Montespan, Harald Wodrich and colleagues http://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1006217 Commented in an opinion paper (GEMS Journal of Virology) http://jvi.asm.org/content/early/2017/06/23/JVI.00581-17.abstract |
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Tingaud-Sequeira A, Raldúa D, Lavie J, Mathieu G, Bordier M, Knoll-Gellida A, Rambeau P, Coupry I, André M, Malm E, Möller C, Andreasson S, Rendtorff ND, Tranebjærg L, Koenig M, Lacombe D, Goizet C, Babin PJ. Neurobiology of Disease 98, 36-51, 2017. doi: 10.1016/j.nbd.2016.11.008. PMID: 27890673 |
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mTORC1 inhibition in cancer cells protects from glutaminolysis-mediated apoptosis during nutrient limitation |
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Focus sur le projet « CHIMIOKINES » du LAMC – L’INSERM U1029 |
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Komatsu T, Robinson DR, Hisaoka M, Ueshima S, Okuwaki M, Nagata K, Wodrich H. |
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Le livre « Une brève Histoire du Vaisseau Sanguin et lymphatique » est sorti le 23 juin en librairie et a été écrit par Andreas Bikfalvi, directeur de l’unité Inserm U 1029 Laboratoire de l’Angiogenèse et du Microenvironnement des Cancers. |
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« Apelin: an antithrombotic factor that inhibits platelet function ».Adam F, Khatib AM, Lopez JJ, Vatier C, Turpin S, Muscat A, Soulet F, Aries A, Jardin I, Bobe R, Stepanian A, de Prost D, Dray C, Rosado JA, Valet P, Feve B, Siegfried G. |
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« CBL controls a tyrosine kinase network involving AXL, SYK and LYN in nilotinib-resistant chronic myeloid leukaemia ».Gioia R, Trégoat C, Dumas PY, Lagarde V, Prouzet-Mauléon V, Desplat V, Sirvent A, Praloran V, Lippert E, Villacreces A, Leconet W, Robert B, Vigon I, Roche S, Mahon FX, Pasquet JM. J Pathol. 2015 May 12. |
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« hRAD51, un modulateur central de l’intégration du VIH-1 ».Sylvain Thierry1*, Mohamed Salah Benleulmi2¶*, Ludivine Sinzelle2, Eloise Thierry1, Christina Calmels2¶, Stephane Chaignepain3, Pierre Waffo-Teguo4, Jean-Michel Merillon4, Brian Budke5, Jean-Max Pasquet6, Simon Litvak2, Angela Ciuffi7, Patrick Sung8, Philip Connell5, Ilona Hauber9¶, Joachim Hauber9¶, Marie-Line Andreola2¶, Olivier Delelis1, Vincent Parissi2# |
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« Intasome architecture and chromatin density modulate retroviral integration into nucleosome ». Mohamed Salah Benleulmi1, Julien Matysiak1, Daniel Rodrigo Henriquez2, Cédric Vaillant3, Paul Lesbats1,8, Christina Calmels1, Monica Naughtin4,9, Oscar Leon2, Anna Marie Skalka5, Marc Ruff6, Marc Lavigne3,7, Marie-Line Andreola1 and Vincent Parissi1* |
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Khatib AM, Lahlil R, Hagedorn M, Delomenie C, Christophe O, Denis C, Siegfried G. Biological outcome and mapping of total factor cascades in response to HIF induction during regenerative angiogenesis. Oncotarget. 2016 Mar 15;7(11):12102-20. doi: 10.18632/oncotarget.7728. |
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Delphine Fessart , Charlotte Domblides, Tony Avril, Leif A Eriksson, Hugues Begueret, Raphael Pineau, Camille Malrieux, Nathalie Dugot-Senant, Carlo Lucchesi, Eric Chevet, Frederic Delom Université de Bordeaux, France; University of Rennes 1, France; University of Gothenburg, Sweden; Hôpital Haut-Lévêque, France; Bergonié Cancer Institute, France
Elife. 2016 May 30;5. pii: e13887. doi: 10.7554/eLife.13887. [Epub ahead of print] |
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Escudero JA, Loot C, Parissi V, Nivina A, Bouchier C, Mazel D. Nat Commun. 2016 Mar 10;7:10937. doi: 10.1038/ncomms10937. |
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Mentions Légales |